Taking Fingerprints of DNA Polymerases: Multiplex Enzyme Profiling on DNA Arrays
نویسندگان
چکیده
منابع مشابه
Taking fingerprints of DNA polymerases: multiplex enzyme profiling on DNA arrays.
A novel screening approach based on an oligonucleotide-addressing enzyme assay enables multiplexed simultaneous profiling of DNA polymerases in nanoliter volumes in terms of their different properties. This approach was used to identify enzymes with altered properties out of a library of protein mutants.
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ژورنال
عنوان ژورنال: Angewandte Chemie International Edition
سال: 2009
ISSN: 1433-7851,1521-3773
DOI: 10.1002/anie.200900953